Endocrine Abstracts

The demonstration in extrathyroidal tissues of the sodium iodide symporter (NIS) has raised the possibility that 131I, commonly used as a therapeutic ablative agent in hyperthyroidism and thyroid cancer, might be applied in the treatment of tumours in other NIS expressing tissues such as human breast cancer. As thyroidal uptake of 131I is known to be inversely proportional to circulating stable I- concentration, the aim of this study was to determine how I- would effect such u...